South Africa has restricted Pakistan to a 270-run total after Pakistan captain Babar Azam won the toss and opted to bat in their World Cup match against in-form Proteas in Chennai on Friday.
Pakistan has lost three matches in succession after winning their first two. They were forced to leave out fast bowler Hasan Ali who has a fever.
He is replaced by Mohammad Wasim while spinner Mohammad Nawaz comes in for Usama Mir in a like-for-like change.
South Africa is in a strong position with four wins in five games.
Their captain Temba Bavuma is back after missing the last two games with a gastric problem.
Opener Reeza Hendricks has made way in one of three changes to the side that defeated Bangladesh by 149 runs in Mumbai on Tuesday.
Kagiso Rabada, who has a back injury, and Lizaad Williams are replaced by leg spinner Tabraiz Shamsi and fast bowler Lungi Ngidi.
Pakistan: Imam-ul-Haq, Abdullah Shafique, Babar Azam (capt), Mohammad Rizwan (wk), Saud Shakeel, Iftikhar Ahmed, Shadab Khan, Mohammad Nawaz, Shaheen Shah Afridi, Mohammad Wasim, Haris Rauf
South Africa: Temba Bavuma (capt), Quinton de Kock (wkt), Rassie van der Dussen, Aiden Markram, Heinrich Klaasen, David Miller, Marco Jansen, Gerald Coetzee, Keshav Maharaj, Tabraiz Shamsi, Lungi Ngidi
Umpires: Alex Wharf (ENG) and Paul Reiffel (AUS)
Tv umpire: Richard Illingworth (ENG)
Match referee: Richie Richardson (WIS)
