At least 12 people were killed and 20 others were injured on Wednesday evening when a bus bound for the flood-hit area of Khairpur Nathan Shah caught fire on the highway near Nooriabad.
Police said that a bus carrying more than 50 flood survivors, who had sought temporary shelter in Karachi, were returning to their homes in flood-hit Khairpur Nathan Shah.
Official added that while travelling on the M-9 Motorway near Nooriabad just near Hyderabad, the bus suddenly caught fire.
Images captured by survivors and passersby from the site showed the night sky lit up with a fire that stretched across a short segment of the highway leading to the bus.
Following the incident, a fire brigade was rushed to the spot. A police squad also reached the site.
The fire brigade put out the blaze in the bus while ambulances shifted the dead and injured to a nearby hospital.
Police said that the cause of the fire has yet to be ascertained. They feared that the casualties may rise.
Sindh Chief Minister Murad Ali Shah expressed grief over the news and directed the Jamshoro Deputy Commissioner and Senior Superintendent of Police to provide the survivors with all possible support apart from mobilizing emergency services to provide medical attention to the injured.