Sergio Ramos was sent off for the 28th time in his career as Paris St-Germain was held by Reims.
Before halftime, the former Real Madrid defender got into an altercation with the referee and received two yellow cards in quick succession.
Without Lionel Messi, missing the game due to injury, PSG needed a strong save from Gianluigi Donnarumma to stop Arber Zeneli.
Neymar, however, blew a wonderful opportunity to win it for PSG when he rushed through but shot wide.
Neymar and Kylian Mbappe both received yellow cards for fouls as the game grew tense toward the conclusion as the visitors began to become frustrated.
The Ligue 1 leaders, who are three points ahead of second-placed Marseille, have only lost points twice this season.
Reims, who have won just once in 10 games so far this season, are 14th.